About the Authors

Atsuyasu Sato

Affiliation Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, United States of America

Machiko Ikegami

machiko.ikegami@cchmc.org

Affiliation Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, United States of America

Competing Interests

The study was supported by Chiesi Farmaceutici S.p.A. The surfactant CHF5633 was supplied by Chiesi Farmaceutici S.p.A. CHF5633 is the new totally synthetic surfactant synthesized by Chiesi Farmaceutici S.p.A (Parma, Italy) for the treatment of preterm newborn infants with RDS. There are no other patents, products in development or other marketed products to declare. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: MI AS. Performed the experiments: MI AS. Analyzed the data: MI AS. Contributed reagents/materials/analysis tools: MI AS. Wrote the paper: MI AS. Other: MI AS.