About the Authors

Lei Shang

Affiliation Institute for Cellular and Molecular Biology, Center for Computational Biology and Bioinformatics, The University of Texas at Austin, Austin, Texas, United States of America

Weijia Xu

Affiliation Texas Advanced Computing Center, The University of Texas at Austin, Austin, Texas, United States of America

Stuart Ozer

Affiliation Microsoft Corporation, Redmond, Washington, United States of America

Robin R. Gutell

robin.gutell@mail.utexas.edu

Affiliation Institute for Cellular and Molecular Biology, Center for Computational Biology and Bioinformatics, The University of Texas at Austin, Austin, Texas, United States of America

Competing Interests

Microsoft Research provided an external research grant to RRG. Although one of the authors, SO, is employed by Microsoft, this does not alter the authors’ adherence to all PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: LS WX SO RRG. Analyzed the data: LS WX SO RRG. Wrote the paper: LS WX SO RRG.