About the Authors

Nao Nishida

nishida-75@umin.ac.jp

Affiliations Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, Ichikawa, Chiba, Japan, Department of Human Genetics, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

Hiromi Sawai

Affiliation Department of Human Genetics, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

Kentaro Matsuura

Affiliation Department of Virology and Liver Unit, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan

Masaya Sugiyama

Affiliation Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, Ichikawa, Chiba, Japan

Sang Hoon Ahn

Affiliation Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea

Jun Yong Park

Affiliation Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea

Shuhei Hige

Affiliation Department of Internal Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan

Jong-Hon Kang

Affiliation Department of Internal Medicine, Teine Keijinkai Hospital, Sapporo, Japan

Kazuyuki Suzuki

Affiliation Department of Gastroenterology and Hepatology, Iwate Medical University, Morioka, Japan

Masayuki Kurosaki

Affiliation Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan

Yasuhiro Asahina

Affiliation Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan

Satoshi Mochida

Affiliation Division of Gastroenterology and Hepatology, Saitama Medical University, Saitama, Japan

Masaaki Watanabe

Affiliation Department of Gastroenterology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan

Eiji Tanaka

Affiliation Department of Medicine, Shinshu University School of Medicine, Matsumoto, Japan

Masao Honda

Affiliation Department of Gastroenterology, Kanazawa University Graduate School of Medicine, Kanazawa, Japan

Shuichi Kaneko

Affiliation Department of Gastroenterology, Kanazawa University Graduate School of Medicine, Kanazawa, Japan

Etsuro Orito

Affiliation Department of Gastroenterology, Nagoya Daini Red Cross Hospital, Nagoya, Japan

Yoshito Itoh

Affiliation Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Kyoto, Japan

Eiji Mita

Affiliation Department of Gastroenterology and Hepatology, National Hospital Organization Osaka National Hospital, Osaka, Japan

Akihiro Tamori

Affiliation Department of Hepatology, Osaka City University Graduate School of Medicine, Osaka, Japan

Yoshikazu Murawaki

Affiliation Second Department of Internal Medicine, Faculty of Medicine, Tottori University, Yonago, Japan

Yoichi Hiasa

Affiliation Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan

Isao Sakaida

Affiliation Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan

Masaaki Korenaga

Affiliation Division of Hepatology and Pancreatology, Kawasaki Medical College, Kurashiki, Japan

Keisuke Hino

Affiliation Division of Hepatology and Pancreatology, Kawasaki Medical College, Kurashiki, Japan

Tatsuya Ide

Affiliation Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Fukuoka, Japan

Minae Kawashima

Affiliation Department of Human Genetics, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

Yoriko Mawatari

Affiliations Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, Ichikawa, Chiba, Japan, Department of Human Genetics, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

Megumi Sageshima

Affiliation Department of Human Genetics, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

Yuko Ogasawara

Affiliation Department of Human Genetics, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

Asako Koike

Affiliation Central Research Laboratory, Hitachi Ltd., Kokubunji, Tokyo, Japan

Namiki Izumi

Affiliation Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan

Kwang-Hyub Han

Affiliation Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea

Yasuhito Tanaka

Affiliation Department of Virology and Liver Unit, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan

Katsushi Tokunaga

Affiliation Department of Human Genetics, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

Masashi Mizokami

Affiliation Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, Ichikawa, Chiba, Japan

Competing Interests

AK is an employee of the Central Research Laboratory, Hitachi Ltd. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: NN HS YT. Performed the experiments: HS Y. Mawatari M. Sageshima YO. Analyzed the data: NN MK AK. Contributed reagents/materials/analysis tools: KM M. Sugiyama SHA JYP SH JHK KS M. Kurosaki YA SM MW ET MH SK EO YI EM AT Y. Murawaki YH IS M. Korenaga KH TI NI KHH YT MM. Wrote the paper: NN M. Kawashima YT KT MM.