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Research Article

Iodine-131 Dose Dependent Gene Expression in Thyroid Cancers and Corresponding Normal Tissues Following the Chernobyl Accident

  • Michael Abend mail,

    michaelabend@bundeswehr.org

    Affiliation: Bundeswehr Institute of Radiobiology, Munich, Germany

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  • Ruth M. Pfeiffer,

    Affiliation: Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, United States of America

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  • Christian Ruf,

    Affiliation: Bundeswehr Institute of Radiobiology, Munich, Germany

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  • Maureen Hatch,

    Affiliation: Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, United States of America

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  • Tetiana I. Bogdanova,

    Affiliation: Institute of Endocrinology and Metabolism, Kyiv, Ukraine

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  • Mykola D. Tronko,

    Affiliation: Institute of Endocrinology and Metabolism, Kyiv, Ukraine

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  • Armin Riecke,

    Affiliation: Bundeswehr Institute of Radiobiology, Munich, Germany

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  • Julia Hartmann,

    Affiliation: Bundeswehr Institute of Radiobiology, Munich, Germany

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  • Viktor Meineke,

    Affiliation: Bundeswehr Institute of Radiobiology, Munich, Germany

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  • Houda Boukheris,

    Affiliation: NOVA Research Company, Bethesda, Maryland, United States of America

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  • Alice J. Sigurdson,

    Affiliation: Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, United States of America

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  • Kiyohiko Mabuchi,

    Affiliation: Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, United States of America

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  • Alina V. Brenner

    Affiliation: Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, United States of America

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  • Published: July 25, 2012
  • DOI: 10.1371/journal.pone.0039103

About the Authors

Michael Abend, Christian Ruf, Armin Riecke, Julia Hartmann, Viktor Meineke
Bundeswehr Institute of Radiobiology, Munich, Germany
Ruth M. Pfeiffer
Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, United States of America
Maureen Hatch, Alice J. Sigurdson, Kiyohiko Mabuchi, Alina V. Brenner
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, United States of America
Tetiana I. Bogdanova, Mykola D. Tronko
Institute of Endocrinology and Metabolism, Kyiv, Ukraine
Houda Boukheris
NOVA Research Company, Bethesda, Maryland, United States of America

Corresponding Author

Email: michaelabend@bundeswehr.org

Competing Interests

The authors herewith declare that one of the co-authors being recently employed by NOVA Research Company does not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials. The coauthor was working at Radiation Epidemiology Branch/National Cancer Institute (REB/NCI) before she changed to NOVA Research Company where she is employed now. At the time of Radiation Epidemiology Branch/National Cancer Institute (REB/NCI) she did her contribution.

Author Contributions

Conceived and designed the experiments: MA RMP CR MH AR JH HB AVB. Performed the experiments: MA CR AR JH. Analyzed the data: MA RMP AVB. Contributed reagents/materials/analysis tools: TIB MDT AJS KM VM. Wrote the paper: MA RMP AVB MH.