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Research Article

Genome-Wide Bovine H3K27me3 Modifications and the Regulatory Effects on Genes Expressions in Peripheral Blood Lymphocytes

  • Yanghua He,

    Affiliation: Key Laboratory of Agricultural Animal Genetics and Breeding, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, P.R. China

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  • Ying Yu mail,

    yuying@cau.edu.cn (YY); changy@cau.edu.cn (YZ)

    Affiliation: Key Laboratory of Agricultural Animal Genetics and Breeding, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, P.R. China

    X
  • Yuan Zhang mail,

    yuying@cau.edu.cn (YY); changy@cau.edu.cn (YZ)

    Affiliation: Key Laboratory of Agricultural Animal Genetics and Breeding, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, P.R. China

    X
  • Jiuzhou Song,

    Affiliation: Department of Animal and Avian Sciences, University of Maryland, College Park, Maryland, United States of America

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  • Apratim Mitra,

    Affiliation: Department of Animal and Avian Sciences, University of Maryland, College Park, Maryland, United States of America

    X
  • Yi Zhang,

    Affiliation: Key Laboratory of Agricultural Animal Genetics and Breeding, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, P.R. China

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  • Yachun Wang,

    Affiliation: Key Laboratory of Agricultural Animal Genetics and Breeding, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, P.R. China

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  • Dongxiao Sun,

    Affiliation: Key Laboratory of Agricultural Animal Genetics and Breeding, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, P.R. China

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  • Shengli Zhang

    Affiliation: Key Laboratory of Agricultural Animal Genetics and Breeding, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, P.R. China

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  • Published: June 28, 2012
  • DOI: 10.1371/journal.pone.0039094

About the Authors

Yanghua He, Ying Yu, Yuan Zhang, Yi Zhang, Yachun Wang, Dongxiao Sun, Shengli Zhang
Key Laboratory of Agricultural Animal Genetics and Breeding, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, P.R. China
Jiuzhou Song, Apratim Mitra
Department of Animal and Avian Sciences, University of Maryland, College Park, Maryland, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YY Yuan Zhang. Performed the experiments: YH. Analyzed the data: YH. Wrote the paper: YH YY. Contributed materials: YW Yi Zhang. Contributed analysis tools: JS AM DS SZ.