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Research Article

Epicutaneous Exposure to Staphylococcal Superantigen Enterotoxin B Enhances Allergic Lung Inflammation via an IL-17A Dependent Mechanism

  • Jinho Yu,

    Affiliation: Division of Allergy and Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Min Hee Oh,

    Affiliation: Division of Allergy and Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Ju-Un Park,

    Affiliation: Division of Allergy and Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Allen C. Myers,

    Affiliation: Division of Allergy and Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Chen Dong,

    Affiliation: Department of Immunology, Center for Inflammation and Cancer, MD Anderson Cancer Center, Houston, Texas, United States of America

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  • Zhou Zhu,

    Affiliation: Division of Allergy and Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Tao Zheng mail

    tzheng@jhmi.edu

    Affiliation: Division of Allergy and Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Published: July 27, 2012
  • DOI: 10.1371/journal.pone.0039032

About the Authors

Jinho Yu, Min Hee Oh, Ju-Un Park, Allen C. Myers, Zhou Zhu, Tao Zheng
Division of Allergy and Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
Chen Dong
Department of Immunology, Center for Inflammation and Cancer, MD Anderson Cancer Center, Houston, Texas, United States of America

Corresponding Author

Email: tzheng@jhmi.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TZ. Performed the experiments: JHY MHO JUP ZZ. Analyzed the data: TZ JHY MHO JUP ZZ. Contributed reagents/materials/analysis tools: ZZ CD ACM. Wrote the paper: TZ.