About the Authors

Agnieszka Smolinska

A.Smolinska@science.ru.nl

Affiliation Institute for Molecules and Materials, Radboud University Nijmegen, Nijmegen, The Netherlands

Lionel Blanchet

Affiliation Institute for Molecules and Materials, Radboud University Nijmegen, Nijmegen, The Netherlands

Leon Coulier

Affiliation TNO Quality of Life, Zeist, The Netherlands

Kirsten A. M. Ampt

Affiliation Institute for Molecules and Materials, Radboud University Nijmegen, Nijmegen, The Netherlands

Theo Luider

Affiliation Department of Neurology, Erasmus University Medical Centre, Rotterdam, The Netherlands

Rogier Q. Hintzen

Affiliation Department of Neurology, Erasmus University Medical Centre, Rotterdam, The Netherlands

Sybren S. Wijmenga

Affiliation Institute for Molecules and Materials, Radboud University Nijmegen, Nijmegen, The Netherlands

Lutgarde M. C. Buydens

Affiliation Institute for Molecules and Materials, Radboud University Nijmegen, Nijmegen, The Netherlands

Competing Interests

LC is employed by TNO quality of Life and our study was funded by TI Pharma. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: AS LB KAMA RQH TL SSW LMCB LC. Performed the experiments: AS KAMA LC. Analyzed the data: AS LB. Contributed reagents/materials/analysis tools: RQH TL. Wrote the paper: AS LB KAMA RQH TL SSW LMCB LC. Diagnosed patients and collected samples and agreements: RQH.