About the Authors
- Clive Ballard
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* E-mail: Clive.ballard@kcl.ac.uk
Affiliation Wolfson Centre for Age-Related Diseases, King’s College London, London, United Kingdom
- Emma Jones
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Affiliation Wolfson Centre for Age-Related Diseases, King’s College London, London, United Kingdom
- Nathan Gauge
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Affiliation Wolfson Centre for Age-Related Diseases, King’s College London, London, United Kingdom
- Dag Aarsland
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Affiliations Department of Neurobiology, Ward and Society, Karolinska Institute, Stockholm, Sweden, Norway, Faculty of Science and Technology, Stavanger University Hospital, Stavanger, Norway
- Odd Bjarte Nilsen
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Affiliation Faculty of Science and Technology, Stavanger University Hospital, Stavanger, Norway
- Brian K. Saxby
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Affiliation Institute of Ageing and Health, University of Newcastle, Newcastle, United Kingdom
- David Lowery
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Affiliation Research Department of Primary Care and Population Health, University College London, London, United Kingdom
- Anne Corbett
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Affiliation Research Directorate, Alzheimer’s Society (UK), London, United Kingdom
- Keith Wesnes
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Affiliation Centre for Human Psychopharmacology, Swinburne University, Melbourne, Australia
- Eirini Katsaiti
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Affiliation Wolfson Centre for Age-Related Diseases, King’s College London, London, United Kingdom
- James Arden
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Affiliation Department of Anaesthetics, King’s College Hospital, London, United Kingdom
- Derek Amaoko
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Affiliation Department of Anaesthetics, King’s College Hospital, London, United Kingdom
- Nicholas Prophet
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Affiliation Department of Anaesthetics, King’s College Hospital, London, United Kingdom
- Balaji Purushothaman
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Affiliation Department of Anaesthetics, King’s College Hospital, London, United Kingdom
- David Green
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Affiliation Department of Anaesthetics, King’s College Hospital, London, United Kingdom
Competing Interests
David Green has received honoraria and expenses for meetings organised by Covidien Inc, manufacturers of the BIS and Invos monitors. Keith Wesnes has a commercial interest in the computerized cognitive assessment battery used in the trial—the Cognitive Drug Research battery. None of the others have any conflicts of interest. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: CB EJ DA BKS DL KW DG. Performed the experiments: EJ NG BKS DL JA DA NP BP DG. Analyzed the data: NG OBN EK. Contributed reagents/materials/analysis tools: BKS KW DG. Wrote the paper: CB EJ NG DA OBN BKS DL AC KW EK JA DA NP BP DG. Interpreting data: CB EJ NG AC DG. Literature search: CB EJ NG DA DL AC EK DG.