About the Authors

Ariadna Mendoza-Naranjo

d.becker@ucl.ac.uk (DLB); a.mendoza@ucl.ac.uk (AMN)

Affiliation Department of Cell and Developmental Biology, University College London, London, United Kingdom

Peter Cormie

Affiliation Department of Cell and Developmental Biology, University College London, London, United Kingdom

Antonio E. Serrano

Affiliation Department of Cell and Developmental Biology, University College London, London, United Kingdom

Rebecca Hu

Affiliation CoDa Therapeutics, Auckland, New Zealand

Shay O'Neill

Affiliation CoDa Therapeutics, Auckland, New Zealand

Chiuhui Mary Wang

Affiliation Department of Cell and Developmental Biology, University College London, London, United Kingdom

Christopher Thrasivoulou

Affiliation Department of Cell and Developmental Biology, University College London, London, United Kingdom

Kieran T. Power

Affiliation Department of Cell and Developmental Biology, University College London, London, United Kingdom

Alexis White

Affiliation CoDa Therapeutics, Auckland, New Zealand

Thomas Serena

Affiliation Newbridge Medical Research Corp, Warren, Pennsylvania, United States of America

Anthony R. J. Phillips

Affiliation CoDa Therapeutics, Auckland, New Zealand

David L. Becker

d.becker@ucl.ac.uk (DLB); a.mendoza@ucl.ac.uk (AMN)

Affiliation Department of Cell and Developmental Biology, University College London, London, United Kingdom

Competing Interests

The authors have read the journal's policy and have the following conflicts: The patented antisense technology targeting Cx43 is being developed by CoDa Therapeutics Inc which is currently in phase2B clinical trial treating venous leg ulcers. Patent: DL Becker and CR Green PCT No. WO 00/44409 USA No. PCT/GB00/00238 Formulations comprising antisense nucleotides to connexins. New Zealand patent 513154 awarded, Australia 21193, USA09/890363, Canada 2361251, Europe 901236 and Japan 00/595711. DLB holds shares in CoDa and RH, SO, AW and ARJP are employed by CoDa. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: AMN ARJP DLB. Performed the experiments: AMN PC AES RH SO CMW CT KTP TS DLB. Analyzed the data: AMN AES RH CT DLB. Contributed reagents/materials/analysis tools: TS AW ARJP. Wrote the paper: AMN ARJP DLB. Obtained ethics for human tissue: TS AW.