About the Authors
- Ariadna Mendoza-Naranjo
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* E-mail: d.becker@ucl.ac.uk (DLB); a.mendoza@ucl.ac.uk (AMN)
Affiliation Department of Cell and Developmental Biology, University College London, London, United Kingdom
- Peter Cormie
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Affiliation Department of Cell and Developmental Biology, University College London, London, United Kingdom
- Antonio E. Serrano
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Affiliation Department of Cell and Developmental Biology, University College London, London, United Kingdom
- Rebecca Hu
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Affiliation CoDa Therapeutics, Auckland, New Zealand
- Shay O'Neill
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Affiliation CoDa Therapeutics, Auckland, New Zealand
- Chiuhui Mary Wang
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Affiliation Department of Cell and Developmental Biology, University College London, London, United Kingdom
- Christopher Thrasivoulou
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Affiliation Department of Cell and Developmental Biology, University College London, London, United Kingdom
- Kieran T. Power
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Affiliation Department of Cell and Developmental Biology, University College London, London, United Kingdom
- Alexis White
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Affiliation CoDa Therapeutics, Auckland, New Zealand
- Thomas Serena
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Affiliation Newbridge Medical Research Corp, Warren, Pennsylvania, United States of America
- Anthony R. J. Phillips
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Affiliation CoDa Therapeutics, Auckland, New Zealand
- David L. Becker
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* E-mail: d.becker@ucl.ac.uk (DLB); a.mendoza@ucl.ac.uk (AMN)
Affiliation Department of Cell and Developmental Biology, University College London, London, United Kingdom
Competing Interests
The authors have read the journal's policy and have the following conflicts: The patented antisense technology targeting Cx43 is being developed by CoDa Therapeutics Inc which is currently in phase2B clinical trial treating venous leg ulcers. Patent: DL Becker and CR Green PCT No. WO 00/44409 USA No. PCT/GB00/00238 Formulations comprising antisense nucleotides to connexins. New Zealand patent 513154 awarded, Australia 21193, USA09/890363, Canada 2361251, Europe 901236 and Japan 00/595711. DLB holds shares in CoDa and RH, SO, AW and ARJP are employed by CoDa. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: AMN ARJP DLB. Performed the experiments: AMN PC AES RH SO CMW CT KTP TS DLB. Analyzed the data: AMN AES RH CT DLB. Contributed reagents/materials/analysis tools: TS AW ARJP. Wrote the paper: AMN ARJP DLB. Obtained ethics for human tissue: TS AW.