About the Authors

Rickson C. Mesquita

Affiliations Department of Physics & Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Institute of Physics, University of Campinas, Campinas, Sao Paulo, Brazil

Sung Wan Han

Affiliation Department of Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Joann Miller

Affiliation Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Steven S. Schenkel

Affiliation Department of Physics & Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Andrew Pole

Affiliation Department of Mathematical Sciences, New Jersey Institute of Technology, Newark, New Jersey, United States of America

Tatiana V. Esipova

Affiliation Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Sergei A. Vinogradov

Affiliation Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Mary E. Putt

Affiliation Department of Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Arjun G. Yodh

Affiliation Department of Physics & Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Theresa M. Busch

buschtm@mail.med.upenn.edu

Affiliation Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Competing Interests

TMB has consulted on PDT for Pharmacyclics and Medivation; however, these arrangements did not provide support for, nor was there relevance to, the area of investigation in this report. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: TMB RCM AGY SAV. Performed the experiments: JM SSS RCM. Analyzed the data: SWH AP MEP RCM TVE. Wrote the paper: TMB RCM.