About the Authors

Yoosoo Chang

Contributed equally to this work with: Yoosoo Chang, Seungho Ryu

Affiliations Department of Occupational Medicine, Kangbuk Samsung Hospital and Sungkyunkwan University School of Medicine, Seoul, South Korea, Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America, Health Screening Center, Kangbuk Samsung Hospital and Sungkyunkwan University School of Medicine, Seoul, South Korea

Seungho Ryu

Contributed equally to this work with: Yoosoo Chang, Seungho Ryu

Affiliations Department of Occupational Medicine, Kangbuk Samsung Hospital and Sungkyunkwan University School of Medicine, Seoul, South Korea, Health Screening Center, Kangbuk Samsung Hospital and Sungkyunkwan University School of Medicine, Seoul, South Korea

Yiyi Zhang

Affiliations Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America, Department of Medicine and Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America

Hee Jung Son

Affiliations Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America, Department of Internal Medicine, Samsung Medical Center and Sungkyunkwan University School of Medicine, Seoul, South Korea

Jang-Young Kim

Affiliations Department of Cardiology, Wonju College of Medicine, Yonsei University, Wonju, South Korea, Institute of Genomic Cohort, Yonsei University, Wonju, South Korea

Juhee Cho

Affiliations Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America, Department of Medicine and Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America, Samsung Comprehensive Cancer Center, Samsung Medical Center, Seoul, South Korea

Eliseo Guallar

eguallar@jhsph.edu

Affiliations Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America, Department of Medicine and Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America, Area of Cardiovascular Epidemiology and Population Genetics, National Center for Cardiovascular Research (CNIC), Madrid, Spain

Competing Interests

The authors have read the journal's policy and have the following conflicts: Drs. Chang and Ryu are employed by the Kangbuk Samsung Hospital and Drs. Son and Cho are employed by the Samsung Medical Center. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: YC SR EG. Performed the experiments: YC SR YZ EG. Analyzed the data: YC SR YZ. Wrote the paper: YC SR YZ HJS JYK JC EG.