About the Authors

Maria H. M. Lima

Affiliation Department of Nursing, FCM, University of Campinas, Campinas, São Paulo, Brazil

Andréa M. Caricilli

Affiliation Department of Internal Medicine, FCM, University of Campinas, Campinas, São Paulo, Brazil

Lélia L. de Abreu

Affiliation Department of Nursing, FCM, University of Campinas, Campinas, São Paulo, Brazil

Eliana P. Araújo

Affiliation Department of Nursing, FCM, University of Campinas, Campinas, São Paulo, Brazil

Fabiana F. Pelegrinelli

Affiliation Department of Internal Medicine, FCM, University of Campinas, Campinas, São Paulo, Brazil

Ana C. P. Thirone

Affiliation Department of Internal Medicine, FCM, University of Campinas, Campinas, São Paulo, Brazil

Daniela M. Tsukumo

Affiliation Department of Internal Medicine, FCM, University of Campinas, Campinas, São Paulo, Brazil

Ana Flávia M. Pessoa

Affiliation Department of Cell and Developmental Biology, University of São Paulo, São Paulo, Brazil

Marinilce F. dos Santos

Affiliation Department of Cell and Developmental Biology, University of São Paulo, São Paulo, Brazil

Maria A. de Moraes

Affiliation Department of Internal Medicine, FCM, University of Campinas, Campinas, São Paulo, Brazil

José B. C. Carvalheira

Affiliation Department of Internal Medicine, FCM, University of Campinas, Campinas, São Paulo, Brazil

Lício A. Velloso

Affiliation Department of Internal Medicine, FCM, University of Campinas, Campinas, São Paulo, Brazil

Mario J. A. Saad

msaad@fcm.unicamp.br

Affiliation Department of Internal Medicine, FCM, University of Campinas, Campinas, São Paulo, Brazil

Competing Interests

The authors have declared that the insulin cream is patented (PI: 0705370-3). However, this does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MHML JBCC LAV MJAS. Performed the experiments: MHML AMC LLA EPA FFP ACPT DMT AFMP MFS. Analyzed the data: LAV JBCC MAM MJAS MFS. Contributed reagents/materials/analysis tools: LAV JBCC MJAS. Wrote the paper: MHML MJAS AMC FFP.