About the Authors
- Li Peng
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Contributed equally to this work with: Li Peng, Michael D. Oberst
Affiliation Department of Antibody Discovery and Protein Engineering, MedImmune LLC, Gaithersburg, Maryland, United States of America
- Michael D. Oberst
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Contributed equally to this work with: Li Peng, Michael D. Oberst
Affiliation Preclinical Oncology, MedImmune LLC, Gaithersburg, Maryland, United States of America
- Jiaqi Huang
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Affiliation Translational Sciences, MedImmune LLC, Gaithersburg, Maryland, United States of America
- Philip Brohawn
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Affiliation Translational Sciences, MedImmune LLC, Gaithersburg, Maryland, United States of America
- Chris Morehouse
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Affiliation Translational Sciences, MedImmune LLC, Gaithersburg, Maryland, United States of America
- Kristen Lekstrom
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Affiliation Department of Antibody Discovery and Protein Engineering, MedImmune LLC, Gaithersburg, Maryland, United States of America
- Patrick A. Baeuerle
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Affiliation Amgen Research (Munich) GmbH, Munich, Germany
- Herren Wu
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Affiliation Department of Antibody Discovery and Protein Engineering, MedImmune LLC, Gaithersburg, Maryland, United States of America
- Yihong Yao
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Affiliation Translational Sciences, MedImmune LLC, Gaithersburg, Maryland, United States of America
- Steven R. Coats
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Affiliation Department of Antibody Discovery and Protein Engineering, MedImmune LLC, Gaithersburg, Maryland, United States of America
- William Dall’Acqua
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Affiliation Department of Antibody Discovery and Protein Engineering, MedImmune LLC, Gaithersburg, Maryland, United States of America
- Melissa Damschroder
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* E-mail: damschroderm@medimmune.com (MD); hammonds@medimmune.com (SH)
Affiliation Department of Antibody Discovery and Protein Engineering, MedImmune LLC, Gaithersburg, Maryland, United States of America
- Scott A. Hammond
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* E-mail: damschroderm@medimmune.com (MD); hammonds@medimmune.com (SH)
Affiliation Preclinical Oncology, MedImmune LLC, Gaithersburg, Maryland, United States of America
Competing Interests
P. Baeuerle is an employee of Micromet, Inc. All other authors are employees of MedImmune LLC. MedImmune and Micromet have several patent applications pending relating to MEDI-565 (a product in development). This does not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors.
Author Contributions
Conceived and designed the experiments: LP MO JH MD SH. Performed the experiments: LP MO JH P. Brohawn CM. Analyzed the data: LP MO JH P. Brohawn CM MD SH. Contributed reagents/materials/analysis tools: KL. Wrote the paper: LP MO MD SH. Supervised the study: P. Baeuerle HW YY SC WD. Approved the manuscript: P. Baeuerle HW YY SC WD.