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Research Article

Integrated Analysis of Gene Expression and Tumor Nuclear Image Profiles Associated with Chemotherapy Response in Serous Ovarian Carcinoma

  • Yuexin Liu,

    Affiliation: Departments of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

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  • Yan Sun,

    Affiliations: Departments of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America, Department of Pathology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China

    X
  • Russell Broaddus,

    Affiliation: Departments of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

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  • Jinsong Liu,

    Affiliation: Departments of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

    X
  • Anil K. Sood,

    Affiliation: Departments of Gynecologic Oncology and Reproductive Medicine and Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

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  • Ilya Shmulevich,

    Affiliation: The Institute for Systems Biology, Seattle, Washington, United States of America

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  • Wei Zhang mail

    wzhang@mdanderson.org

    Affiliation: Departments of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

    X
  • Published: May 08, 2012
  • DOI: 10.1371/journal.pone.0036383

About the Authors

Yuexin Liu, Yan Sun, Russell Broaddus, Jinsong Liu, Wei Zhang
Departments of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
Anil K. Sood
Departments of Gynecologic Oncology and Reproductive Medicine and Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
Yan Sun
Department of Pathology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
Ilya Shmulevich
The Institute for Systems Biology, Seattle, Washington, United States of America

Corresponding Author

Email: wzhang@mdanderson.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YXL WZ. Performed the experiments: YXL YS. Analyzed the data: YXL YS RB JSL AKS IS WZ. Contributed reagents/materials/analysis tools: YXL WZ. Wrote the paper: YXL YS RB JSL AKS IS WZ. Designed the software used in analysis: YXL.