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Research Article

Choline Dehydrogenase Polymorphism rs12676 Is a Functional Variation and Is Associated with Changes in Human Sperm Cell Function

  • Amy R. Johnson,

    Affiliation: Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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  • Sai Lao,

    Affiliation: Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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  • Tongwen Wang,

    Affiliations: Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Nutrition Research Institute, Gillings School of Global Public Health and School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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  • Joseph A. Galanko,

    Affiliation: Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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  • Steven H. Zeisel mail

    steven_zeisel@unc.edu

    Affiliations: Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Nutrition Research Institute, Gillings School of Global Public Health and School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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  • Published: April 27, 2012
  • DOI: 10.1371/journal.pone.0036047

About the Authors

Amy R. Johnson, Sai Lao, Tongwen Wang, Steven H. Zeisel
Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
Joseph A. Galanko
Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
Tongwen Wang, Steven H. Zeisel
Nutrition Research Institute, Gillings School of Global Public Health and School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

Corresponding Author

Email: steven_zeisel@unc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ARJ SHZ. Performed the experiments: ARJ SL TW. Analyzed the data: ARJ JAG SHZ. Wrote the paper: ARJ SHZ.