About the Authors
- Munehisa Yabuki
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Contributed equally to this work with: Munehisa Yabuki, W. Jason Cummings
Current address: Omeros Corporation, Seattle, Washington, United States of America
Affiliations Department of Immunology, University of Washington School of Medicine, Seattle, Washington, United States of America, XORI Corporation, Seattle, Washington, United States of America
- W. Jason Cummings
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Contributed equally to this work with: Munehisa Yabuki, W. Jason Cummings
Current address: Omeros Corporation, Seattle, Washington, United States of America
Affiliations Department of Immunology, University of Washington School of Medicine, Seattle, Washington, United States of America, XORI Corporation, Seattle, Washington, United States of America
- John B. Leppard
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Current address: Boehringer Ingelheim, Ridgefield, Connecticut, United States of America
Affiliation XORI Corporation, Seattle, Washington, United States of America
- Robert M. Immormino
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Current address: Department of Microbiology, University of North Carolina, Chapel Hill, North Carolina, United States of America
Affiliation Department of Immunology, University of Washington School of Medicine, Seattle, Washington, United States of America
- Christi L. Wood
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Current address: Omeros Corporation, Seattle, Washington, United States of America
Affiliation XORI Corporation, Seattle, Washington, United States of America
- Daniel S. Allison
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Current address: Alder Biopharmaceuticals, Bothell, Washington, United States of America
Affiliation XORI Corporation, Seattle, Washington, United States of America
- Patrick W. Gray
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Current address: Omeros Corporation, Seattle, Washington, United States of America
Affiliation Accelerator Corporation, Seattle, Washington, United States of America
- Larry W. Tjoelker
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Current address: Omeros Corporation, Seattle, Washington, United States of America
Affiliation XORI Corporation, Seattle, Washington, United States of America
- Nancy Maizels
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* E-mail: maizels@u.washington.edu
Affiliations Department of Immunology, University of Washington School of Medicine, Seattle, Washington, United States of America, Department of Biochemistry, University of Washington School of Medicine, Seattle, Washington, United States of America
Competing Interests
Some authors (MY, WJC, JBL, CLW, DSA, PWG, LWT and NM) declare competing financial interests as they are or have been employed at or are stockholders in XORI Corporation, Omeros Corporation, Boehringer Ingelheim, Alder Biopharmaceuticals or Accelerator Corporation. NM, WJC and MY are inventors of the platform used in this research and described in patent Inducible Mutagenesis of Target Genes (WO2009029315). Patent applications have been filed relating to the anti-FN14 antibodies, the anti-FZD10 antibodies, and the VH targeting method. The authors confirm here that these interests will not alter adherence to PLoS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: MY WJC JBL DSA PWG LWT NM. Performed the experiments: MY WJC JBL RMI CLW DSA LWT. Wrote the paper: MY WJC LWT NM. Assisted in writing the manuscript: JBL RMI CLW DSA PWG.