About the Authors

Xuejian Xiong

Contributed equally to this work with: Xuejian Xiong, Daniel N. Frank

Affiliation Program in Molecular Structure and Function, The Hospital for Sick Children, Toronto, Canada

Daniel N. Frank

Contributed equally to this work with: Xuejian Xiong, Daniel N. Frank

Affiliation Division of Infectious Diseases, University of Colorado, Aurora, Colorado, United States of America

Charles E. Robertson

Affiliation Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, Colorado, United States of America

Stacy S. Hung

Affiliations Program in Molecular Structure and Function, The Hospital for Sick Children, Toronto, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Canada

Janet Markle

Affiliations Department of Immunology, University of Toronto, Toronto, Canada, Program in Genetics and Genomic Biology, The Hospital for Sick Children, Toronto, Canada

Angelo J. Canty

Affiliation Department of Mathematics and Statistics, McMaster University, Hamilton, Canada

Kathy D. McCoy

Affiliation Department Klinische Forschung, University of Bern, Bern, Switzerland

Andrew J. Macpherson

Affiliation Department Klinische Forschung, University of Bern, Bern, Switzerland

Philippe Poussier

Affiliations Department of Immunology, University of Toronto, Toronto, Canada, Sunnybrook Health Sciences Centre Research Institute, University of Toronto, Toronto, Canada

Jayne S. Danska

Affiliations Department of Immunology, University of Toronto, Toronto, Canada, Program in Genetics and Genomic Biology, The Hospital for Sick Children, Toronto, Canada, Department of Medical Biophysics, University of Toronto, Toronto, Canada

John Parkinson

jparkin@sickkids.ca

Affiliations Program in Molecular Structure and Function, The Hospital for Sick Children, Toronto, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Canada, Department of Biochemistry, University of Toronto, Toronto, Canada

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JP DNF PP JSD. Performed the experiments: XX DNF CER JM. Analyzed the data: XX DNF CER JP. Contributed reagents/materials/analysis tools: SSH AJC KDM AJM. Wrote the paper: DNF PP JSD JP.