About the Authors

Michelangela Barbieri

Contributed equally to this work with: Michelangela Barbieri, Clara Di Filippo

Affiliation Department of Geriatric Medicine and Metabolic Diseases, Second University of Naples, Naples, Italy

Clara Di Filippo

Contributed equally to this work with: Michelangela Barbieri, Clara Di Filippo

Affiliation Department of Experimental Medicine, Section of Pharmacology L. Donatelli, Second University of Naples, Naples, Italy

Antonietta Esposito

Affiliation Department of Geriatric Medicine and Metabolic Diseases, Second University of Naples, Naples, Italy

Raffaele Marfella

Affiliation Department of Geriatric Medicine and Metabolic Diseases, Second University of Naples, Naples, Italy

Maria Rosaria Rizzo

Affiliation Department of Geriatric Medicine and Metabolic Diseases, Second University of Naples, Naples, Italy

Michele D'Amico

Affiliation Department of Experimental Medicine, Section of Pharmacology L. Donatelli, Second University of Naples, Naples, Italy

Franca Ferraraccio

Affiliation Department of Preventive Medicine, Second University of Naples, Naples, Italy

Cristina Di Ronza

Affiliation Department of Experimental Medicine, Section of Pharmacology L. Donatelli, Second University of Naples, Naples, Italy

Sheng Zhong Duan

Affiliation Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China

Richard M. Mortensen

Affiliation Metabolism, Endocrinology and Diabetes Division, Departments of Molecular and Integrative Physiology, Pharmacology, and Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

Francesco Rossi

Affiliation Department of Experimental Medicine, Section of Pharmacology L. Donatelli, Second University of Naples, Naples, Italy

Giuseppe Paolisso

giuseppe.paolisso@unina2.it

Affiliation Department of Geriatric Medicine and Metabolic Diseases, Second University of Naples, Naples, Italy

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MB CDF AE RM MRR MDA FR GP SZD. Performed the experiments: MB CDF AE RM MDA FF CDR SZD RMM. Analyzed the data: MB RM MRR GP FR MDA CDF AE RMM. Contributed reagents/materials/analysis tools: MB CDF GP FF MDA. Wrote the paper: MB CDF MR MRR GP. Performed anatomy pathology analysis: FF. Participated in the creation of PPAR-γ–knockout (CM-PGKO) mice: SZD RMM.