Overexpression of Angiopoietin-1 Increases CD133+/c-kit+ Cells and Reduces Myocardial Apoptosis in db/db Mouse Infarcted Hearts

Heng Zeng; Lanfang Li; Jian-Xiong Chen

doi:10.1371/journal.pone.0035905

Loading metrics

Open Access

Peer-reviewed

Research Article

Overexpression of Angiopoietin-1 Increases CD133+/c-kit+ Cells and Reduces Myocardial Apoptosis in db/db Mouse Infarcted Hearts

Heng Zeng,

Affiliation Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi, United States of America
⨯
Lanfang Li,

Affiliation Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi, United States of America
⨯
Jian-Xiong Chen

* E-mail: JChen3@umc.edu

Affiliation Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi, United States of America
⨯

Overexpression of Angiopoietin-1 Increases CD133+/c-kit+ Cells and Reduces Myocardial Apoptosis in db/db Mouse Infarcted Hearts

Heng Zeng,
Lanfang Li,
Jian-Xiong Chen

Published: April 27, 2012
https://doi.org/10.1371/journal.pone.0035905

About the Authors

Heng Zeng

Affiliation Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi, United States of America

Lanfang Li

Affiliation Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi, United States of America

Jian-Xiong Chen

* E-mail: JChen3@umc.edu

Affiliation Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JX. Performed the experiments: HZ LL. Analyzed the data: HZ LL JX. Contributed reagents/materials/analysis tools: JX. Wrote the paper: JX.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Heart
Is the Subject Area "Heart" applicable to this article?

Thanks for your feedback.
Diabetes mellitus
Is the Subject Area "Diabetes mellitus" applicable to this article?

Thanks for your feedback.
Ischemia
Is the Subject Area "Ischemia" applicable to this article?

Thanks for your feedback.
Hyperexpression techniques
Is the Subject Area "Hyperexpression techniques" applicable to this article?

Thanks for your feedback.
DAPI staining
Is the Subject Area "DAPI staining" applicable to this article?

Thanks for your feedback.
Myocardial infarction
Is the Subject Area "Myocardial infarction" applicable to this article?

Thanks for your feedback.
Apoptosis
Is the Subject Area "Apoptosis" applicable to this article?

Thanks for your feedback.
Angiogenesis
Is the Subject Area "Angiogenesis" applicable to this article?

Thanks for your feedback.