About the Authors

Billy Chen

Contributed equally to this work with: Billy Chen, Lin Zhong

Affiliation Molecular Medicine Program, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America

Lin Zhong

Contributed equally to this work with: Billy Chen, Lin Zhong

Affiliation Division of Cardiovascular Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Sarah F. Roush

Affiliation Division of Cardiovascular Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Laura Pentassuglia

Affiliation Division of Cardiovascular Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Xuyang Peng

Affiliation Division of Cardiovascular Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Susan Samaras

Affiliation Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Jeffrey M. Davidson

Affiliations Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Research Service, Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, United Sates of America

Douglas B. Sawyer

Affiliation Division of Cardiovascular Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Chee Chew Lim

chee.lim@vanderbilt.edu

Affiliation Division of Cardiovascular Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Competing Interests

The authors have read the journal's policy and have the following conflicts: DBS has received grant support from Genentech, Inc., Roch, Inc., and Acorda Therapuetics, Inc. DBS has been a consultant for Oncothyreon, Millenium Pharmaceuticals, and Regeneron. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: BC LZ CCL. Performed the experiments: BC LZ SFR LP. Analyzed the data: BC LZ CCL. Contributed reagents/materials/analysis tools: XP SS JMD DBS CCL. Wrote the paper: BC CCL.