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Research Article

Widespread Contribution of Gdf7 Lineage to Cerebellar Cell Types and Implications for Hedgehog-Driven Medulloblastoma Formation

  • Frances Y. Cheng equal contributor,

    equal contributor Contributed equally to this work with: Frances Y. Cheng, Xi Huang

    Affiliation: Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

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  • Xi Huang equal contributor,

    equal contributor Contributed equally to this work with: Frances Y. Cheng, Xi Huang

    Affiliation: Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

    Current address: Howard Hughes Medical Institute, Departments of Physiology, Biophysics and Biochemistry, University of California San Francisco, San Francisco, California, United States of America

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  • Anuraag Sarangi,

    Affiliation: Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

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  • Tatiana Ketova,

    Affiliation: Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

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  • Michael K. Cooper,

    Affiliation: Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

    X
  • Ying Litingtung,

    Affiliation: Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

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  • Chin Chiang mail

    chin.chiang@vanderbilt.edu

    Affiliations: Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Neuroscience Program, Vanderbilt University, Nashville, Tennessee, United States of America

    X
  • Published: April 23, 2012
  • DOI: 10.1371/journal.pone.0035541

About the Authors

Frances Y. Cheng, Xi Huang, Tatiana Ketova, Ying Litingtung, Chin Chiang
Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
Anuraag Sarangi, Michael K. Cooper
Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
Chin Chiang
Neuroscience Program, Vanderbilt University, Nashville, Tennessee, United States of America

Corresponding Author

Email: chin.chiang@vanderbilt.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: FYC XH YL CC. Performed the experiments: FYC XH AS TK. Analyzed the data: FYC XH YL CC. Contributed reagents/materials/analysis tools: AS MC. Wrote the paper: FYC XH CC.