About the Authors

Yumiko Wada

ywada@syntapharma.com

Affiliation Synta Pharmaceuticals Corp, Lexington, Massachusetts, United States of America

Irma Cardinale

Affiliation Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, United States of America

Artemis Khatcherian

Affiliation Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, United States of America

John Chu

Affiliation Synta Pharmaceuticals Corp, Lexington, Massachusetts, United States of America

Aaron B. Kantor

Affiliation Biomarker Discovery Sciences, Pharmaceutical Product Development Inc., Menlo Park, California, United States of America

Alice B. Gottlieb

Affiliation Department of Dermatology, Tufts Medical Center, Boston, Massachusetts, United States of America

Noriaki Tatsuta

Affiliation Synta Pharmaceuticals Corp, Lexington, Massachusetts, United States of America

Eric Jacobson

Affiliation Synta Pharmaceuticals Corp, Lexington, Massachusetts, United States of America

James Barsoum

Affiliation Synta Pharmaceuticals Corp, Lexington, Massachusetts, United States of America

James G. Krueger

Affiliation Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, United States of America

Competing Interests

The authors have read the journal’s policy and have the following conflicts: YW, NT, EJ and JB are current or former employees of Synta Pharmaceuticals Corp.; JGK received an honorarium for lecturing from Synta Pharmaceuticals Corp. This does not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials. There are no other competing interests to declare.

Author Contributions

Conceived and designed the experiments: YW ABK EJ JB JGK. Performed the experiments: IC AK JC ABG. Analyzed the data: YW ABK NT JGK. Wrote the paper: YW JGK.