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Research Article

Genetic Polymorphism in a VEGF-Independent Angiogenesis Gene ANGPT1 and Overall Survival of Colorectal Cancer Patients after Surgical Resection

  • Jingyao Dai,

    Affiliation: Department of Hepatobiliary Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China

    X
  • Shaogui Wan,

    Affiliation: Division of Population Science, Department of Medical Oncology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

    X
  • Feng Zhou,

    Affiliation: Department of General Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an, China

    X
  • Ronald E. Myers,

    Affiliation: Division of Population Science, Department of Medical Oncology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

    X
  • Xu Guo,

    Affiliation: State Key Laboratory of Cancer Biology, Cell Engineering Research Center & Department of Cell Biology, The Fourth Military Medical University, Xi'an, China

    X
  • Bingshan Li,

    Affiliation: Center for Human Genetics Research, Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, Tennessee, United States of America

    X
  • Xiaoying Fu,

    Affiliation: Division of Population Science, Department of Medical Oncology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

    X
  • Juan P. Palazzo,

    Affiliation: Department of Pathology, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

    X
  • Kefeng Dou,

    Affiliation: Department of Hepatobiliary Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China

    X
  • Hushan Yang mail,

    hushan.yang@jefferson.edu (HY); xingjl@fmmu.edu.cn (JX)

    Affiliation: Division of Population Science, Department of Medical Oncology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

    X
  • Jinliang Xing mail

    hushan.yang@jefferson.edu (HY); xingjl@fmmu.edu.cn (JX)

    Affiliation: State Key Laboratory of Cancer Biology, Cell Engineering Research Center & Department of Cell Biology, The Fourth Military Medical University, Xi'an, China

    X
  • Published: April 04, 2012
  • DOI: 10.1371/journal.pone.0034758

About the Authors

Jingyao Dai, Kefeng Dou
Department of Hepatobiliary Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China
Shaogui Wan, Ronald E. Myers, Xiaoying Fu, Hushan Yang
Division of Population Science, Department of Medical Oncology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
Feng Zhou
Department of General Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an, China
Xu Guo, Jinliang Xing
State Key Laboratory of Cancer Biology, Cell Engineering Research Center & Department of Cell Biology, The Fourth Military Medical University, Xi'an, China
Bingshan Li
Center for Human Genetics Research, Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, Tennessee, United States of America
Juan P. Palazzo
Department of Pathology, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JLX. Performed the experiments: JYD SW XF. Analyzed the data: FZ REM XG BSL KFD. Contributed reagents/materials/analysis tools: JPP KFD. Wrote the paper: JYD HSY.