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Research Article

A Multi-Cancer Mesenchymal Transition Gene Expression Signature Is Associated with Prolonged Time to Recurrence in Glioblastoma

  • Wei-Yi Cheng,

    Affiliations: Center for Computational Biology and Bioinformatics, Columbia University, New York, New York, United States of America, Department of Electrical Engineering, Columbia University, New York, New York, United States of America

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  • Jessica J. Kandel,

    Affiliations: Institute for Cancer Genetics, Columbia University, New York, New York, United States of America, Department of Surgery, Columbia University, New York, New York, United States of America, Department of Pediatrics, Columbia University, New York, New York, United States of America

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  • Darrell J. Yamashiro,

    Affiliations: Institute for Cancer Genetics, Columbia University, New York, New York, United States of America, Department of Pediatrics, Columbia University, New York, New York, United States of America, Department of Pathology and Cell Biology, Columbia University, New York, New York, United States of America

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  • Peter Canoll,

    Affiliations: Department of Pathology and Cell Biology, Columbia University, New York, New York, United States of America, Columbia Stem Cell Initiative, Columbia University, New York, New York, United States of America

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  • Dimitris Anastassiou mail

    da8@columbia.edu

    Affiliations: Center for Computational Biology and Bioinformatics, Columbia University, New York, New York, United States of America, Department of Electrical Engineering, Columbia University, New York, New York, United States of America

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  • Published: April 06, 2012
  • DOI: 10.1371/journal.pone.0034705

About the Authors

Wei-Yi Cheng, Dimitris Anastassiou
Center for Computational Biology and Bioinformatics, Columbia University, New York, New York, United States of America
Jessica J. Kandel, Darrell J. Yamashiro
Institute for Cancer Genetics, Columbia University, New York, New York, United States of America
Jessica J. Kandel
Department of Surgery, Columbia University, New York, New York, United States of America
Jessica J. Kandel, Darrell J. Yamashiro
Department of Pediatrics, Columbia University, New York, New York, United States of America
Darrell J. Yamashiro, Peter Canoll
Department of Pathology and Cell Biology, Columbia University, New York, New York, United States of America
Peter Canoll
Columbia Stem Cell Initiative, Columbia University, New York, New York, United States of America
Wei-Yi Cheng, Dimitris Anastassiou
Department of Electrical Engineering, Columbia University, New York, New York, United States of America

Corresponding Author

Email: da8@columbia.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: WYC DA. Performed the experiments: WYC DA. Analyzed the data: WYC JJK DJY PC DA. Wrote the paper: DA.