About the Authors

Ekaterina Y. Lukianova-Hleb

Affiliation Department of Biochemistry and Cell Biology, Rice University, Houston, Texas, United States of America

Xiaoyang Ren

Affiliation Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Pamela E. Constantinou

Affiliation Department of Biochemistry and Cell Biology, Rice University, Houston, Texas, United States of America

Brian P. Danysh

Affiliation Department of Biochemistry and Cell Biology, Rice University, Houston, Texas, United States of America

Derek L. Shenefelt

Affiliation Department of Biochemistry and Cell Biology, Rice University, Houston, Texas, United States of America

Daniel D. Carson

Affiliation Department of Biochemistry and Cell Biology, Rice University, Houston, Texas, United States of America

Mary C. Farach-Carson

Affiliation Department of Biochemistry and Cell Biology, Rice University, Houston, Texas, United States of America

Vladimir A. Kulchitsky

Affiliation Institute of Physiology, National Academy of Science of Belarus, Minsk, Belarus

Xiangwei Wu

Affiliation Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Daniel S. Wagner

Affiliation Department of Biochemistry and Cell Biology, Rice University, Houston, Texas, United States of America

Dmitri O. Lapotko

dl5@rice.edu

Affiliations Department of Biochemistry and Cell Biology, Rice University, Houston, Texas, United States of America, Department of Physics and Astronomy, Rice University, Houston, Texas, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Wrote the paper: EYLH DSW DOL. Conceived the mechanism of cell targeting as the nanoparticle cluster – plasmonic nanobubble threshold effect and designed the experimental set up: DOL. Designed cell models and discussed the results: DDC MCFC VAK XW DSW EYLH DOL. Performed the experiments (prepared and characterized the cells): EYLH XR PEC BPD DLS. Performed the experiments (characterized the nanoparticles and plasmonic nanobubbles): EYLH DOL.