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Research Article

Plakophilin-3 Is Required for Late Embryonic Amphibian Development, Exhibiting Roles in Ectodermal and Neural Tissues

  • William A. Munoz,

    Affiliations: Department of Biochemistry and Molecular Biology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America, Program in Genes and Development, University of Texas Graduate School of Biomedical Science, Houston, Texas, United States of America

    X
  • Malgorzata Kloc,

    Affiliations: Department of Biochemistry and Molecular Biology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America, Department of Surgery, The Methodist Hospital Research Institute, Houston, Texas, United States of America

    X
  • Kyucheol Cho equal contributor,

    equal contributor Contributed equally to this work with: Kyucheol Cho, Moonsup Lee

    Affiliations: Department of Biochemistry and Molecular Biology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America, Program in Genes and Development, University of Texas Graduate School of Biomedical Science, Houston, Texas, United States of America

    X
  • Moonsup Lee equal contributor,

    equal contributor Contributed equally to this work with: Kyucheol Cho, Moonsup Lee

    Affiliations: Department of Biochemistry and Molecular Biology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America, Program in Genes and Development, University of Texas Graduate School of Biomedical Science, Houston, Texas, United States of America

    X
  • Ilse Hofmann,

    Affiliation: Joint Research Division Vascular Biology of the Medical Faculty Mannheim, University of Heidelberg- DKFZ, Mannheim, Germany

    X
  • Amy Sater,

    Affiliation: Biology and Biochemistry Department, University of Houston, Houston, Texas, United States of America

    X
  • Kris Vleminckx,

    Affiliation: Department for Molecular Biomedical Research, Flanders Institute for Biotechnology VIB, Ghent, Belgium

    X
  • Pierre D. McCrea mail

    pdmccrea@mdanderson.org

    Affiliations: Department of Biochemistry and Molecular Biology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America, Program in Genes and Development, University of Texas Graduate School of Biomedical Science, Houston, Texas, United States of America

    X
  • Published: April 05, 2012
  • DOI: 10.1371/journal.pone.0034342

About the Authors

William A. Munoz, Malgorzata Kloc, Kyucheol Cho, Moonsup Lee, Pierre D. McCrea
Department of Biochemistry and Molecular Biology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
William A. Munoz, Kyucheol Cho, Moonsup Lee, Pierre D. McCrea
Program in Genes and Development, University of Texas Graduate School of Biomedical Science, Houston, Texas, United States of America
Malgorzata Kloc
Department of Surgery, The Methodist Hospital Research Institute, Houston, Texas, United States of America
Ilse Hofmann
Joint Research Division Vascular Biology of the Medical Faculty Mannheim, University of Heidelberg- DKFZ, Mannheim, Germany
Amy Sater
Biology and Biochemistry Department, University of Houston, Houston, Texas, United States of America
Kris Vleminckx
Department for Molecular Biomedical Research, Flanders Institute for Biotechnology VIB, Ghent, Belgium

Corresponding Author

Email: pdmccrea@mdanderson.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: WAM KC ML IH MK PDM KV. Performed the experiments: WAM KC ML MK. Analyzed the data: WAM KC ML MK PDM AS. Contributed reagents/materials/analysis tools: IH MK AS KV. Wrote the paper: WAM PDM.