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Research Article

Cannabinoid Receptor 2-Mediated Attenuation of CXCR4-Tropic HIV Infection in Primary CD4+ T Cells

  • Cristina Maria Costantino,

    Affiliations: Department of Infectious Diseases, Department of Medicine, Immunology Institute, Mount Sinai School of Medicine, New York, New York, United States of America, Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, New York, United States of America

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  • Achla Gupta,

    Affiliation: Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, New York, United States of America

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  • Alice W. Yewdall,

    Affiliation: Department of Infectious Diseases, Department of Medicine, Immunology Institute, Mount Sinai School of Medicine, New York, New York, United States of America

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  • Benjamin M. Dale,

    Affiliation: Department of Infectious Diseases, Department of Medicine, Immunology Institute, Mount Sinai School of Medicine, New York, New York, United States of America

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  • Lakshmi A. Devi mail,

    Ben.Chen@mssm.edu (BC); Lakshmi.Devi@mssm.edu (LD)

    Affiliation: Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, New York, United States of America

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  • Benjamin K. Chen mail

    Ben.Chen@mssm.edu (BC); Lakshmi.Devi@mssm.edu (LD)

    Affiliation: Department of Infectious Diseases, Department of Medicine, Immunology Institute, Mount Sinai School of Medicine, New York, New York, United States of America

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  • Published: March 20, 2012
  • DOI: 10.1371/journal.pone.0033961

About the Authors

Cristina Maria Costantino, Alice W. Yewdall, Benjamin M. Dale, Benjamin K. Chen
Department of Infectious Diseases, Department of Medicine, Immunology Institute, Mount Sinai School of Medicine, New York, New York, United States of America
Cristina Maria Costantino, Achla Gupta, Lakshmi A. Devi
Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, New York, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CMC BKC LAD. Performed the experiments: CMC AG AWY BD. Analyzed the data: CMC AG. Contributed reagents/materials/analysis tools: CMC AG AWY BD. Wrote the paper: CMC BKC.