About the Authors
- Toshimori Kitami
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Affiliations Broad Institute, Cambridge, Massachusetts, United States of America, Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America
- David J. Logan
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Affiliation Broad Institute, Cambridge, Massachusetts, United States of America
- Joseph Negri
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Affiliation Broad Institute, Cambridge, Massachusetts, United States of America
- Thomas Hasaka
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Affiliation Broad Institute, Cambridge, Massachusetts, United States of America
- Nicola J. Tolliday
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Affiliation Broad Institute, Cambridge, Massachusetts, United States of America
- Anne E. Carpenter
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Affiliation Broad Institute, Cambridge, Massachusetts, United States of America
- Bruce M. Spiegelman
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Affiliation Department of Cell Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America
- Vamsi K. Mootha
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* E-mail: vamsi@hms.harvard.edu
Affiliations Broad Institute, Cambridge, Massachusetts, United States of America, Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America
Competing Interests
The authors have the following conflicts: The project was partly supported by a gift from Nestle Research Center to Dr. Mootha. There are no other declarations concerning Nestle Research Center (employment, consultancy, patents, products, or other competing interests). This gift does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: TK VKM. Performed the experiments: TK JN TH. Analyzed the data: TK DJL AEC NJT VKM. Contributed reagents/materials/analysis tools: BMS. Wrote the paper: TK VKM. Provided guidance: BMS.