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Research Article

Differential Analysis of Ovarian and Endometrial Cancers Identifies a Methylator Phenotype

  • Diana L. Kolbe,

    Affiliation: DIR/GTB Genomic Functional Analysis Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Julie A. DeLoia,

    Affiliations: Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh Medical School, Pittsburgh, Pennsylvania, United States of America, School of Public Health and Health Services, George Washington University, Washington DC, United States of America

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  • Patricia Porter-Gill,

    Affiliation: DIR/GTB Molecular Pathogenesis Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Mary Strange,

    Affiliation: Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh Medical School, Pittsburgh, Pennsylvania, United States of America

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  • Hanna M. Petrykowska,

    Affiliation: DIR/GTB Genomic Functional Analysis Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Alfred Guirguis,

    Affiliation: Department of Obstetrics and Gynecology, Rush University, Chicago, Illinois, United States of America

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  • Thomas C. Krivak,

    Affiliation: Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh Medical School, Pittsburgh, Pennsylvania, United States of America

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  • Lawrence C. Brody,

    Affiliation: DIR/GTB Molecular Pathogenesis Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Laura Elnitski mail

    elnitski@mail.nih.gov

    Affiliation: DIR/GTB Genomic Functional Analysis Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Published: March 05, 2012
  • DOI: 10.1371/journal.pone.0032941

About the Authors

Diana L. Kolbe, Hanna M. Petrykowska, Laura Elnitski
DIR/GTB Genomic Functional Analysis Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America
Patricia Porter-Gill, Lawrence C. Brody
DIR/GTB Molecular Pathogenesis Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America
Julie A. DeLoia, Mary Strange, Thomas C. Krivak
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh Medical School, Pittsburgh, Pennsylvania, United States of America
Julie A. DeLoia
School of Public Health and Health Services, George Washington University, Washington DC, United States of America
Alfred Guirguis
Department of Obstetrics and Gynecology, Rush University, Chicago, Illinois, United States of America

Corresponding Author

Email: elnitski@mail.nih.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Prepared the samples: PPG AG MS HMP. Provided biological consultation and manuscript revision: JAD LCB TCK. Conceived and designed the experiments: JAD LCB LE DLK. Performed the experiments: DLK. Analyzed the data: JAD TCK LCB LE DLK. Contributed reagents/materials/analysis tools: PPG AG MS. Wrote the paper: DLK LE.