About the Authors

Natasja Nielsen

Affiliations Translational Immunology, Novo Nordisk A/S, Måløv, Denmark, Department of Microbiology and Immunology and the Cancer Research Institute, University of California San Francisco, San Francisco, California, United States of America

Niels Ødum

Affiliation Department of Biology, Faculty of Science, University of Copenhagen, Copenhagen, Denmark

Birgitte Ursø

Affiliation Monocyte Biology, Inflammation Biology, Novo Nordisk A/S, Måløv, Denmark

Lewis L. Lanier

Affiliation Department of Microbiology and Immunology and the Cancer Research Institute, University of California San Francisco, San Francisco, California, United States of America

Pieter Spee

spee@novonordisk.com

Affiliation Translational Immunology, Novo Nordisk A/S, Måløv, Denmark

Competing Interests

NN, BU, and PS are employees of Novo Nordisk A/S and own shares. This project was partly supported by Novo Nordisk A/S. PS has assigned patents related to NKG2A and NNC0141-0100 (WO2007042573, 20070726; WO2007147898, 20071227; WO2008009545, 20080124; WO2009092805, 20090730). BU has a patent related to NKG2D (WO09077483, 20090625). LLL and UCSF have licensed intellectual property rights regarding NKG2D for commercial applications. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: NN PS. Performed the experiments: NN. Analyzed the data: NN. Contributed reagents/materials/analysis tools: LLL N BU. Wrote the paper: NN. Supervised research: LLL PS NØ. Edited the paper: LLL PS NØ. Facilitated the study: BU.