About the Authors

Binoy Appukuttan

appukutt@ohsu.edu

Affiliation Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, United States of America

Trevor J. McFarland

Affiliation Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, United States of America

Andrew Stempel

Affiliation Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, United States of America

Jean B. Kassem

Affiliation Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, United States of America

Matthew Hartzell

Affiliation Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, United States of America

Yi Zhang

Affiliation Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, United States of America

Derek Bond

Affiliation Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, United States of America

Kelsey West

Affiliation Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, United States of America

Reid Wilson

Affiliation Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, United States of America

Andrew Stout

Affiliation Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, United States of America

Yuzhen Pan

Affiliation Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, United States of America

Hoda Ilias

Affiliation Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, United States of America

Kathryn Robertson

Affiliation Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, United States of America

Michael L. Klein

Affiliation Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, United States of America

David Wilson

Affiliation Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, United States of America

Justine R. Smith

Affiliation Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, United States of America

J. Timothy Stout

Affiliation Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, United States of America

Competing Interests

The authors have read the journal’s policy and have the following conflicts: Authors BA, TJM and JTS have submitted a patent for the use of RTEF-1 variants as therapy for ocular neovascular disease. Title of patent is: “RTEF-1 variants and the use thereof for inhibition of angiogenesis.” Application number: 12/134,626 Publication number: US 2009/0117119 A1 Filing date: Jun 6, 2008 A link to the patent application is given below: http://www.google.com/patents?id=ZUXGAAAAEBAJ&printsec=frontcover&dq=appukuttan&hl=en&ei=24Q4ToxDzNaIAuOGvPIO&sa=X&oi=book_result&ct=result&resnum=3&sqi=2&ved=0CCwQ6AEwAg. The authors state that this does not alter their adherence to all the PLoS ONE policies on sharing data and materials, as detailed in the guide to authors. In addition, the authors verify that the majority of the experiments/data presented in this manuscript was discovered prior to the filing of the patent and that no personal financial interest will be gained from the publication of the data presented in this manuscript. The authors have obtained funding from the National Institutes of Health to continue experiments on RTEF isoforms and verify that they are presenting the data in an unbiased fashion for peer review. All other authors declare that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BA JTS. Performed the experiments: BA TJM JBK DB YZ KW RW A. Stout HI KR MWH YP A. Stempel. Analyzed the data: BA TJM MWH DJW JRS JTS A. Stempel. Contributed reagents/materials/analysis tools: MLK. Wrote the paper: BA TJM JRS JTS.