About the Authors

Masayoshi Itoh

Contributed equally to this work with: Masayoshi Itoh, Miki Kojima

maitoh@riken.jp (MI); rgscerg@gsc.riken.jp (YH)

Affiliation Omics Science Center, RIKEN Yokohama Institute, Tsurumi-ku, Yokohama, Kanagawa, Japan

Miki Kojima

Contributed equally to this work with: Masayoshi Itoh, Miki Kojima

Affiliation Omics Science Center, RIKEN Yokohama Institute, Tsurumi-ku, Yokohama, Kanagawa, Japan

Sayaka Nagao-Sato

Affiliation K. K. Dnaform, Ono-cho, Tsurumi-ku, Yokohama, Kanagawa, Japan

Eri Saijo

Affiliation K. K. Dnaform, Ono-cho, Tsurumi-ku, Yokohama, Kanagawa, Japan

Timo Lassmann

Affiliation Omics Science Center, RIKEN Yokohama Institute, Tsurumi-ku, Yokohama, Kanagawa, Japan

Mutsumi Kanamori-Katayama

Current address: Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden

Affiliation Omics Science Center, RIKEN Yokohama Institute, Tsurumi-ku, Yokohama, Kanagawa, Japan

Ai Kaiho

Affiliation Omics Science Center, RIKEN Yokohama Institute, Tsurumi-ku, Yokohama, Kanagawa, Japan

Marina Lizio

Affiliation Omics Science Center, RIKEN Yokohama Institute, Tsurumi-ku, Yokohama, Kanagawa, Japan

Hideya Kawaji

Affiliation Omics Science Center, RIKEN Yokohama Institute, Tsurumi-ku, Yokohama, Kanagawa, Japan

Piero Carninci

Affiliation Omics Science Center, RIKEN Yokohama Institute, Tsurumi-ku, Yokohama, Kanagawa, Japan

Alistair R. R. Forrest

Affiliation Omics Science Center, RIKEN Yokohama Institute, Tsurumi-ku, Yokohama, Kanagawa, Japan

Yoshihide Hayashizaki

maitoh@riken.jp (MI); rgscerg@gsc.riken.jp (YH)

Affiliation Omics Science Center, RIKEN Yokohama Institute, Tsurumi-ku, Yokohama, Kanagawa, Japan

Competing Interests

SN-S and ES are employees of K. K. Dnaform. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: MI. Performed the experiments: MK SN-S ES AK. Analyzed the data: HK ML TL. Contributed reagents/materials/analysis tools: MK SN-S ES TL HK. Wrote the paper: MI AF HK TL. Advised for the improvements of protocol: PC AF MK-K. Acquired the fund for this project and approved to publish this work: YH.