About the Authors
- Robert Mintzer
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Affiliation Department of Biochemical Pharmacology, Genentech, Inc., South San Francisco, California, United States of America
- Sreemathy Ramaswamy
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Affiliation Department of Biochemical Pharmacology, Genentech, Inc., South San Francisco, California, United States of America
- Kinjalkumar Shah
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Affiliation Department of Biochemical Pharmacology, Genentech, Inc., South San Francisco, California, United States of America
- Rami N. Hannoush
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Affiliation Department of Early Discovery Biochemistry, Genentech, Inc., South San Francisco, California, United States of America
- Christine D. Pozniak
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Affiliation Department of Neuroscience, Genentech, Inc., South San Francisco, California, United States of America
- Frederick Cohen
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Affiliation Department of Discovery Chemistry, Genentech, Inc., South San Francisco, California, United States of America
- Xianrui Zhao
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Affiliation Department of Discovery Chemistry, Genentech, Inc., South San Francisco, California, United States of America
- Emile Plise
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Affiliation Department of Drug Metabolism and PK, Genentech, Inc., South San Francisco, California, United States of America
- Joseph W. Lewcock
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Affiliation Department of Neuroscience, Genentech, Inc., South San Francisco, California, United States of America
- Christopher E. Heise
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* E-mail: heise.christopher@gene.com
Affiliation Department of Biochemical Pharmacology, Genentech, Inc., South San Francisco, California, United States of America
Competing Interests
All authors are full-time employees of Genentech. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials. There are no patents, products in development, or marketed products to declare.
Author Contributions
Conceived and designed the experiments: RM SR RNH CEH. Performed the experiments: RM SR KS RNH EP. Analyzed the data: RM SR RNH CEH. Contributed reagents/materials/analysis tools: CDP XZ FC JWL. Wrote the paper: RM CEH.