About the Authors
- Marcus O. Butler
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Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Massachusetts, United States of America, Department of Medicine, Brigham and Women's Hospital, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America
- Osamu Imataki
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Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Massachusetts, United States of America, Department of Medicine, Brigham and Women's Hospital, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America
- Yoshihiro Yamashita
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Affiliation Division of Functional Genomics, Jichi Medical University, Tochigi, Japan
- Makito Tanaka
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Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Massachusetts, United States of America, Department of Medicine, Brigham and Women's Hospital, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America
- Sascha Ansén
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Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Massachusetts, United States of America, Department of Medicine, Brigham and Women's Hospital, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America
- Alla Berezovskaya
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Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, Massachusetts, United States of America
- Genita Metzler
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Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, Massachusetts, United States of America
- Matthew I. Milstein
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Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, Massachusetts, United States of America
- Mary M. Mooney
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Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, Massachusetts, United States of America
- Andrew P. Murray
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Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, Massachusetts, United States of America
- Hiroyuki Mano
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Affiliations Division of Functional Genomics, Jichi Medical University, Tochigi, Japan, Department of Medical Genomics, University of Tokyo, Tokyo, Japan
- Lee M. Nadler
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Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Massachusetts, United States of America, Department of Medicine, Brigham and Women's Hospital, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America
- Naoto Hirano
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* E-mail: nhirano@uhnres.utoronto.ca
Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Massachusetts, United States of America, Department of Medicine, Brigham and Women's Hospital, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America, Immune Therapy Program, Campbell Family Institute for Breast Cancer Research, Campbell Family Cancer Research, Ontario Cancer Institute, Toronto, Ontario, Canada, Department of Immunology, University of Toronto, Toronto, Ontario, Canada
Competing Interests
MOB, LMN and NH have filed a patent application related to aAPC/A2. The patent application number is 10/850,294 and is entitled, "Modified Antigen-Presenting Cells." The authors confirm that this application does not alter their adherence to all PLoS ONE policies on the sharing of data and materials.
Author Contributions
Conceived and designed the experiments: MOB LMN NH. Performed the experiments: MOB OI MT SA AB GM MIM MMM APM NH. Analyzed the data: MOB LMN NH. Contributed reagents/materials/analysis tools: MOB OI YY MT SA HM LMN NH. Wrote the paper: MOB LMN NH.