About the Authors

Jan S. Tchorz

Affiliations Novartis Institute for Biomedical Research, Developmental and Molecular Pathways, Novartis Pharma AG, Basel, Switzerland, Department of Biomedicine, Institute of Physiology, University of Basel, Basel, Switzerland

Thomas Suply

Affiliation Novartis Institute for Biomedical Research, Developmental and Molecular Pathways, Novartis Pharma AG, Basel, Switzerland

Iwona Ksiazek

Affiliation Novartis Institute for Biomedical Research, Developmental and Molecular Pathways, Novartis Pharma AG, Basel, Switzerland

Claudio Giachino

Affiliation Max-Planck Institute for Immunobiology, Freiburg, Germany

Dimitri Cloëtta

Affiliation Department of Biomedicine, Institute of Physiology, University of Basel, Basel, Switzerland

Claus-Peter Danzer

Affiliation Novartis Institute for Biomedical Research, Developmental and Molecular Pathways, Novartis Pharma AG, Basel, Switzerland

Thierry Doll

Affiliation Novartis Institute for Biomedical Research, Developmental and Molecular Pathways, Novartis Pharma AG, Basel, Switzerland

Andrea Isken

Affiliation Novartis Institute for Biomedical Research, Developmental and Molecular Pathways, Novartis Pharma AG, Basel, Switzerland

Marianne Lemaistre

Affiliation Novartis Institute for Biomedical Research, Developmental and Molecular Pathways, Novartis Pharma AG, Basel, Switzerland

Verdon Taylor

Affiliations Max-Planck Institute for Immunobiology, Freiburg, Germany, Department of Biomedical Science, Centre for Stem Cell Biology, University of Sheffield, Sheffield, United Kingdom

Bernhard Bettler

Affiliation Department of Biomedicine, Institute of Physiology, University of Basel, Basel, Switzerland

Bernd Kinzel

Affiliation Novartis Institute for Biomedical Research, Developmental and Molecular Pathways, Novartis Pharma AG, Basel, Switzerland

Matthias Mueller

matthias.mueller@novartis.com

Affiliation Novartis Institute for Biomedical Research, Developmental and Molecular Pathways, Novartis Pharma AG, Basel, Switzerland

Competing Interests

Dr. Tchorz, Dr. Suply, Dr. Ksiazek, Dr. Danzer, Dr. Doll, Dr. Isken, Dr. Lemaistre, Dr. Kinzel and Dr. Mueller are employees of Novartis Pharma AG. There are no patents, products in development or marketed products to declare. These authors confirm that this does not alter their adherence to all the PloS ONE policies on sharing data and material.

Author Contributions

Conceived and designed the experiments: JST MM BK BB VT. Performed the experiments: JST TS IK CG DC CPD TD AI ML. Analyzed the data: JST IK CG DC CPD. Wrote the paper: JST BB MM.