About the Authors

Sivananthaperumal Shanmugasundararaj

Affiliation Department of Anesthesia and Critical Care, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Simon Lehle

Current address: Interfaculty Institute of Biochemistry, Department of Molecular Medicine, Eberhard Karls University Tübingen, Tübingen, Germany

Affiliation Department of Anesthesia and Critical Care, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Herve I. Yamodo

Affiliation Department of Anesthesia and Critical Care, Massachusetts General Hospital, Boston, Massachusetts, United States of America

S. Shaukat Husain

Affiliation Department of Anesthesia and Critical Care, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Claire Tseng

Affiliation Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America

Khanh Nguyen

Affiliation Department of Anesthesia and Critical Care, Massachusetts General Hospital, Boston, Massachusetts, United States of America

George H. Addona

Current address: Department of In-vitro Pharmacology, Merck Research Labs, West Point, Pennsylvania, United States of America

Affiliations Department of Anesthesia and Critical Care, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America

Keith W. Miller

k_miller@helix.mgh.harvard.edu

Affiliations Department of Anesthesia and Critical Care, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GA KM. Performed the experiments: SS SL SSH CT KN HY. Analyzed the data: SS SL HY GA KM. Contributed reagents/materials/analysis tools: SSH. Wrote the paper: SS KM.