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Research Article

Uterine Dysfunction in Biglycan and Decorin Deficient Mice Leads to Dystocia during Parturition

  • Zhiping Wu,

    Affiliation: Department of Pediatrics, Women and Infants' Hospital of Rhode Island, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America

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  • Abraham W. Aron,

    Affiliation: Department of Pediatrics, Women and Infants' Hospital of Rhode Island, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America

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  • Elyse E. Macksoud,

    Affiliation: Department of Pediatrics, Women and Infants' Hospital of Rhode Island, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America

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  • Renato V. Iozzo,

    Affiliation: Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

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  • Chi-Ming Hai,

    Affiliation: Department of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, Rhode Island, United States of America

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  • Beatrice E. Lechner mail

    blechner@wihri.org

    Affiliation: Department of Pediatrics, Women and Infants' Hospital of Rhode Island, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America

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  • Published: January 13, 2012
  • DOI: 10.1371/journal.pone.0029627

About the Authors

Zhiping Wu, Abraham W. Aron, Elyse E. Macksoud, Beatrice E. Lechner
Department of Pediatrics, Women and Infants' Hospital of Rhode Island, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America
Renato V. Iozzo
Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
Chi-Ming Hai
Department of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, Rhode Island, United States of America

Corresponding Author

Email: blechner@wihri.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BEL CMH. Performed the experiments: BEL AWA EEM ZW. Analyzed the data: BEL AWA EEM ZW. Contributed reagents/materials/analysis tools: BEL RVI CMH. Wrote the paper: BEL. Helped with the manuscript: RVI AWA ZW.