About the Authors

Alexei A. Podtelezhnikov

Affiliation Exploratory and Translational Sciences, Merck Research Laboratories, Merck Inc., West Point, Pennsylvania, United States of America

Keith Q. Tanis

Affiliation Exploratory and Translational Sciences, Merck Research Laboratories, Merck Inc., West Point, Pennsylvania, United States of America

Michael Nebozhyn

Affiliation Exploratory and Translational Sciences, Merck Research Laboratories, Merck Inc., West Point, Pennsylvania, United States of America

William J. Ray

Affiliation Neuroscience, Merck Research Laboratories, Merck Inc., West Point, Pennsylvania, United States of America

David J. Stone

Contributed equally to this work with: David J. Stone, Andrey P. Loboda

Affiliation Exploratory and Translational Sciences, Merck Research Laboratories, Merck Inc., West Point, Pennsylvania, United States of America

Andrey P. Loboda

Contributed equally to this work with: David J. Stone, Andrey P. Loboda

andrey_loboda@merck.com

Affiliation Exploratory and Translational Sciences, Merck Research Laboratories, Merck Inc., West Point, Pennsylvania, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AP AL WR KT DS. Analyzed the data: AP MN AL. Contributed reagents/materials/analysis tools: MN WR. Wrote the paper: AP AL. Co-senior authors: AL DS.