About the Authors

Catherine Féart

catherine.feart@isped.u-bordeaux2.fr

Affiliations INSERM, U897, Bordeaux, France, Université Bordeaux Segalen, Bordeaux, France

Catherine Helmer

Affiliations INSERM, U897, Bordeaux, France, Université Bordeaux Segalen, Bordeaux, France

Hervé Fleury

Affiliation Université Bordeaux Segalen, Bordeaux, France

Yannick Béjot

Affiliation Department of Neurology, University Hospital of Dijon, Dijon Stroke Registry, EA4184, Faculty of Medicine of Dijon, University of Burgundy, Dijon, France

Karen Ritchie

Affiliations INSERM, U888, Montpellier, France, Faculty of Medicine, Imperial College London, London, United Kingdom

Philippe Amouyel

Affiliations INSERM, UMR744, Lille, France, Institut Pasteur de Lille, University of Lille 2, Lille, France

Susanna Schraen-Maschke

Affiliations Institut Pasteur de Lille, University of Lille 2, Lille, France, INSERM, U837, Lille, France

Luc Buée

Affiliations Institut Pasteur de Lille, University of Lille 2, Lille, France, INSERM, U837, Lille, France

Jean-Charles Lambert

Affiliations INSERM, UMR744, Lille, France, Institut Pasteur de Lille, University of Lille 2, Lille, France

Luc Letenneur

Affiliations INSERM, U897, Bordeaux, France, Université Bordeaux Segalen, Bordeaux, France

Jean-François Dartigues

Affiliations INSERM, U897, Bordeaux, France, Université Bordeaux Segalen, Bordeaux, France

Competing Interests

Sanofi-Aventis has an interest in anti-Amyloid Beta antibody therapy for treating Alzheimer's disease; specifically, an anti-Amyloid Beta antibody therapy is in development. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: CF CH LL JFD. Performed the experiments: CF CH LL JFD. Analyzed the data: CF CH LL JFD JCL KR HF YB PA SSM LB. Contributed reagents/materials/analysis tools: SSM LB JCL PA HF YB. Wrote the paper: CF CH LL JFD. Provided significant advice: HF YB KR PA SSM LB JCL.