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Research Article

Exogenous IFN-alpha Administration Reduces Influenza A Virus Replication in the Lower Respiratory Tract of Rhesus Macaques

  • Shannon R. Matzinger,

    Affiliations: Center for Comparative Medicine, University of California Davis, Davis, California, United States of America, California National Primate Research Center, University of California Davis, Davis, California, United States of America

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  • Timothy D. Carroll,

    Affiliations: Center for Comparative Medicine, University of California Davis, Davis, California, United States of America, California National Primate Research Center, University of California Davis, Davis, California, United States of America

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  • Linda Fritts,

    Affiliations: Center for Comparative Medicine, University of California Davis, Davis, California, United States of America, California National Primate Research Center, University of California Davis, Davis, California, United States of America

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  • Michael B. McChesney,

    Affiliation: Center for Comparative Medicine, University of California Davis, Davis, California, United States of America

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  • Christopher J. Miller mail

    cjmiller@ucdavis.edu

    Affiliations: Center for Comparative Medicine, University of California Davis, Davis, California, United States of America, California National Primate Research Center, University of California Davis, Davis, California, United States of America

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  • Published: December 29, 2011
  • DOI: 10.1371/journal.pone.0029255

About the Authors

Shannon R. Matzinger, Timothy D. Carroll, Linda Fritts, Michael B. McChesney, Christopher J. Miller
Center for Comparative Medicine, University of California Davis, Davis, California, United States of America
Shannon R. Matzinger, Timothy D. Carroll, Linda Fritts, Christopher J. Miller
California National Primate Research Center, University of California Davis, Davis, California, United States of America

Corresponding Author

Email: cjmiller@ucdavis.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CJM MBM. Performed the experiments: SRM TDC LF. Analyzed the data: CJM SRM. Wrote the paper: CJM SRM.