About the Authors

Raphael Rozenfeld

Affiliation Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, New York, United States of America

Ittai Bushlin

Affiliations Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, New York, United States of America, Department of Neuroscience and The Friedman Brain Institute, Mount Sinai School of Medicine, New York, New York, United States of America

Ivone Gomes

Affiliation Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, New York, United States of America

Nikos Tzavaras

Affiliation Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, New York, United States of America

Achla Gupta

Affiliation Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, New York, United States of America

Susana Neves

Affiliations Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, New York, United States of America, Systems Biology Center of New York, Mount Sinai School of Medicine, New York, New York, United States of America

Lorenzo Battini

Affiliation Department of Medicine, Mount Sinai School of Medicine, New York, New York, United States of America

G. Luca Gusella

Affiliation Department of Medicine, Mount Sinai School of Medicine, New York, New York, United States of America

Alexander Lachmann

Affiliations Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, New York, United States of America, Systems Biology Center of New York, Mount Sinai School of Medicine, New York, New York, United States of America

Avi Ma'ayan

Affiliations Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, New York, United States of America, Systems Biology Center of New York, Mount Sinai School of Medicine, New York, New York, United States of America

Robert D. Blitzer

Affiliations Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, New York, United States of America, Systems Biology Center of New York, Mount Sinai School of Medicine, New York, New York, United States of America

Lakshmi A. Devi

lakshmi.devi@mssm.edu

Affiliations Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, New York, United States of America, Department of Neuroscience and The Friedman Brain Institute, Mount Sinai School of Medicine, New York, New York, United States of America, Systems Biology Center of New York, Mount Sinai School of Medicine, New York, New York, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RR IB LD. Performed the experiments: RR IB IG AG SN NT LB GG AL AM. Analyzed the data: RR IB IG NT AL. Contributed reagents/materials/analysis tools: LB GLG NT AL AM RB. Wrote the paper: RR IB IG LD.