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Research Article

Interferon and Biologic Signatures in Dermatomyositis Skin: Specificity and Heterogeneity across Diseases

  • David Wong,

    Affiliation: Department of Dermatology, Stanford University School of Medicine, Stanford, California, United States of America

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  • Bory Kea,

    Affiliation: Department of Dermatology, Stanford University School of Medicine, Stanford, California, United States of America

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  • Rob Pesich,

    Affiliation: Department of Biochemistry, Stanford University School of Medicine, Stanford, California, United States of America

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  • Brandon W. Higgs,

    Affiliation: MedImmune, Translational Sciences, One MedImmune Way, Gaithersburg, Maryland, United States of America

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  • Wei Zhu,

    Affiliation: MedImmune, Translational Sciences, One MedImmune Way, Gaithersburg, Maryland, United States of America

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  • Patrick Brown,

    Affiliation: Department of Biochemistry, Stanford University School of Medicine, Stanford, California, United States of America

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  • Yihong Yao,

    Affiliation: MedImmune, Translational Sciences, One MedImmune Way, Gaithersburg, Maryland, United States of America

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  • David Fiorentino mail

    fiorentino@stanford.edu

    Affiliation: Department of Dermatology, Stanford University School of Medicine, Stanford, California, United States of America

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  • Published: January 03, 2012
  • DOI: 10.1371/journal.pone.0029161

About the Authors

David Wong, Bory Kea, David Fiorentino
Department of Dermatology, Stanford University School of Medicine, Stanford, California, United States of America
Rob Pesich, Patrick Brown
Department of Biochemistry, Stanford University School of Medicine, Stanford, California, United States of America
Brandon W. Higgs, Wei Zhu, Yihong Yao
MedImmune, Translational Sciences, One MedImmune Way, Gaithersburg, Maryland, United States of America

Corresponding Author

Email: fiorentino@stanford.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DW BK DF. Performed the experiments: DW BK RP BH WZ DF. Analyzed the data: DW BK BH YY PB DF. Contributed reagents/materials/analysis tools: DW BK WZ YY PB DF. Wrote the paper: DW BK DF.