About the Authors

Manoj Tyagi

Affiliation National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

Ratna R. Thangudu

Affiliation National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

Dachuan Zhang

Affiliation National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

Stephen H. Bryant

Affiliation National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

Thomas Madej

madej@ncbi.nlm.nih.gov (TM); panch@ncbi.nlm.nih.gov (AP)

Affiliation National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

Anna R. Panchenko

madej@ncbi.nlm.nih.gov (TM); panch@ncbi.nlm.nih.gov (AP)

Affiliation National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AP TM. Analyzed the data: MT. Contributed reagents/materials/analysis tools: DZ. Wrote the paper: MT TM AP. Participated in discussions: SB. Designed the software used in analysis: MT RT DZ.