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Research Article

Multiplexed Quantum Dot Labeling of Activated c-Met Signaling in Castration-Resistant Human Prostate Cancer

  • Peizhen Hu equal contributor,

    equal contributor Contributed equally to this work with: Peizhen Hu, Gina C.-Y. Chu

    Affiliations: Uro-Oncology Research Program, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, United States of America, Department of Pathology, Xijing Hospital, Fourth Military University, Xi'an, China

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  • Gina C.-Y. Chu equal contributor,

    equal contributor Contributed equally to this work with: Peizhen Hu, Gina C.-Y. Chu

    Affiliation: Uro-Oncology Research Program, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, United States of America

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  • Guodong Zhu,

    Affiliation: Department of Urology, The First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an, China

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  • Hua Yang,

    Affiliation: Department of Pathology, Jilin University, Changchun, China

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  • Daniel Luthringer,

    Affiliation: Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, California, United States of America

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  • Gail Prins,

    Affiliation: Department of Physiology, University of Illinois at Chicago, Chicago, Illinois, United States of America

    X
  • Fouad Habib,

    Affiliation: Department of Surgery, The University of Edinburgh, Edinburgh, Scotland

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  • Yuzhuo Wang,

    Affiliation: Department of Experimental Therapeutics, BC Cancer, Vancouver, British Columbia, Canada

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  • Ruoxiang Wang,

    Affiliation: Uro-Oncology Research Program, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, United States of America

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  • Leland W. K. Chung,

    Affiliation: Uro-Oncology Research Program, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, United States of America

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  • Haiyen E. Zhau mail

    Haiyen.zhau@cshs.org

    Affiliation: Uro-Oncology Research Program, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, United States of America

    X
  • Published: December 21, 2011
  • DOI: 10.1371/journal.pone.0028670

About the Authors

Peizhen Hu, Gina C.-Y. Chu, Ruoxiang Wang, Leland W. K. Chung, Haiyen E. Zhau
Uro-Oncology Research Program, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
Peizhen Hu
Department of Pathology, Xijing Hospital, Fourth Military University, Xi'an, China
Guodong Zhu
Department of Urology, The First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an, China
Hua Yang
Department of Pathology, Jilin University, Changchun, China
Daniel Luthringer
Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
Gail Prins
Department of Physiology, University of Illinois at Chicago, Chicago, Illinois, United States of America
Fouad Habib
Department of Surgery, The University of Edinburgh, Edinburgh, Scotland
Yuzhuo Wang
Department of Experimental Therapeutics, BC Cancer, Vancouver, British Columbia, Canada

Corresponding Author

Email: Haiyen.zhau@cshs.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HEZ LWKC GCYC PH GZ. Performed the experiments: PH GCYC GZ HEZ. Analyzed the data: RW PH GCYC HEZ GZ LWKC. Contributed reagents/materials/analysis tools: HY DL GP FH YW. Wrote the paper: HEZ LWKC RW GCYC PH.