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Research Article

A Meta-Analysis of Array-CGH Studies Implicates Antiviral Immunity Pathways in the Development of Hepatocellular Carcinoma

  • Xu Guo equal contributor,

    equal contributor Contributed equally to this work with: Xu Guo, Yanna

    Affiliation: State Key Laboratory of Cancer Biology, Department of Cell Biology, Cell Engineering Research Center, The Fourth Military Medical University, Xi'an, People's Republic of China

    X
  • Yanna equal contributor,

    equal contributor Contributed equally to this work with: Xu Guo, Yanna

    Affiliation: Department of Clinical Immunology, Xijing Hospital, The Fourth Military Medical University, Xi'an, People's Republic of China

    X
  • Xi Ma,

    Affiliation: State Key Laboratory of Cancer Biology, Department of Cell Biology, Cell Engineering Research Center, The Fourth Military Medical University, Xi'an, People's Republic of China

    X
  • Jiaze An,

    Affiliation: Department of Hepatobiliary Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, People's Republic of China

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  • Yukui Shang,

    Affiliation: State Key Laboratory of Cancer Biology, Department of Cell Biology, Cell Engineering Research Center, The Fourth Military Medical University, Xi'an, People's Republic of China

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  • Qichao Huang,

    Affiliation: State Key Laboratory of Cancer Biology, Department of Cell Biology, Cell Engineering Research Center, The Fourth Military Medical University, Xi'an, People's Republic of China

    X
  • Hushan Yang,

    Affiliation: Division of Population Science, Department of Medical Oncology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

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  • Zhinan Chen mail,

    xingjl@fmmu.edu.cn (JX); znchen@fmmu.edu.cn (ZC)

    Affiliation: State Key Laboratory of Cancer Biology, Department of Cell Biology, Cell Engineering Research Center, The Fourth Military Medical University, Xi'an, People's Republic of China

    X
  • Jinliang Xing mail

    xingjl@fmmu.edu.cn (JX); znchen@fmmu.edu.cn (ZC)

    Affiliation: State Key Laboratory of Cancer Biology, Department of Cell Biology, Cell Engineering Research Center, The Fourth Military Medical University, Xi'an, People's Republic of China

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  • Published: December 12, 2011
  • DOI: 10.1371/journal.pone.0028404

About the Authors

Xu Guo, Xi Ma, Yukui Shang, Qichao Huang, Zhinan Chen, Jinliang Xing
State Key Laboratory of Cancer Biology, Department of Cell Biology, Cell Engineering Research Center, The Fourth Military Medical University, Xi'an, People's Republic of China
Yanna
Department of Clinical Immunology, Xijing Hospital, The Fourth Military Medical University, Xi'an, People's Republic of China
Jiaze An
Department of Hepatobiliary Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, People's Republic of China
Hushan Yang
Division of Population Science, Department of Medical Oncology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JLX XM ZNC. Performed the experiments: XG YKS YNB. Analyzed the data: YKS XM YNB. Contributed reagents/materials/analysis tools: QCH JZA YNB. Wrote the paper: XG HSY.