About the Authors

Sid E. O'Bryant

Contributed equally to this work with: Sid E. O'Bryant, Guanghua Xiao

Sid.Obryant@ttuhsc.edu

Affiliation Department of Neurology, F. Marie Hall Institute for Rural and Community Health, Garrison Institute on Aging, Texas Tech University Health Sciences Center, Lubbock, Texas, United States of America

Guanghua Xiao

Contributed equally to this work with: Sid E. O'Bryant, Guanghua Xiao

Affiliation Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

Robert Barber

Affiliation Department of Pharmacology and Neuroscience, Institute for Aging and Alzheimer's Disease Research, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

Ryan Huebinger

Affiliation Department of Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

Kirk Wilhelmsen

Affiliation Department of Genetics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

Melissa Edwards

Affiliation Department of Psychology, Texas Tech University, Lubbock, Texas, United States of America

Neill Graff-Radford

Affiliation Department of Neurology, Mayo Clinic, Jacksonville, Florida, United States of America

Rachelle Doody

Affiliation Department of Neurology, Alzheimer's Disease and Memory Disorders Center, Baylor College of Medicine, Houston, Texas, United States of America

Ramon Diaz-Arrastia

Affiliation Center for Neuroscience and Regenerative Medicine, Uniformed Services University of the Health Sciences, Rockville, Maryland, United States of America

for the Texas Alzheimer's Research & Care Consortium

Current address: For a full list of the investigators from the Texas Alzheimer's Research Consortium please see the Acknowledgments section

for the Alzheimer's Disease Neuroimaging Initiative

Current address: For more information about the Alzheimer's Disease Neuroimaging Initiative please see the Acknowledgments section

Competing Interests

The authors have the following competing interest: In the TARC, a patent has been submitted on this blood-based screener. There are no other products in development or marketed products to declare. This does not alter the authors' adherence to all PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors. ADNI has received funding from the following commercial sources: Abbott, AstraZeneca AB, Bayer Schering Pharma AG, Bristol-Myers Squibb, Eisai Global Clinical Development, Elan Corporation, Genentech, GE Healthcare, GlaxoSmithKline, Innogenetics, Johnson and Johnson, Eli Lilly and Co., Medpace, Inc., Merck and Co., Inc., Novartis AG, Pfizer Inc, F. Hoffman-La Roche, Schering-Plough, Synarc, Inc. This does not alter the authors' adherence to all PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors. ADNI data is freely available to any interested scientists.

Author Contributions

Conceived and designed the experiments: SEO GX RB RD RDA. Performed the experiments: SEO GX RB KW RD RDA. Analyzed the data: SEO GX RB RH KW ME NGR RD RDA. Contributed reagents/materials/analysis tools: SEO GX RB KW RD RDA. Wrote the paper: SEO GX RB RH KW ME NGR RD RDA.