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Research Article

A Higher-Order Generalized Singular Value Decomposition for Comparison of Global mRNA Expression from Multiple Organisms

  • Sri Priya Ponnapalli,

    Affiliation: Department of Electrical and Computer Engineering, University of Texas at Austin, Texas, United States of America

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  • Michael A. Saunders,

    Affiliation: Department of Management Science and Engineering, Stanford University, Stanford, California, United States of America

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  • Charles F. Van Loan,

    Affiliation: Department of Computer Science, Cornell University, Ithaca, New York, United States of America

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  • Orly Alter mail

    orly@sci.utah.edu

    Affiliation: Scientific Computing and Imaging (SCI) Institute and Departments of Bioengineering and Human Genetics, University of Utah, Salt Lake City, Utah, United States of America

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  • Published: December 22, 2011
  • DOI: 10.1371/journal.pone.0028072

About the Authors

Sri Priya Ponnapalli
Department of Electrical and Computer Engineering, University of Texas at Austin, Texas, United States of America
Michael A. Saunders
Department of Management Science and Engineering, Stanford University, Stanford, California, United States of America
Charles F. Van Loan
Department of Computer Science, Cornell University, Ithaca, New York, United States of America
Orly Alter
Scientific Computing and Imaging (SCI) Institute and Departments of Bioengineering and Human Genetics, University of Utah, Salt Lake City, Utah, United States of America

Corresponding Author

Email: orly@sci.utah.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: OA. Performed the experiments: SPP OA. Analyzed the data: SPP OA. Contributed reagents/materials/analysis tools: SPP OA. Wrote the paper: SPP MAS CFVL OA. Proved mathematical theorems: SPP MAS CFVL OA.