About the Authors

Twila A. Mason

Affiliations Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

Elena Kolobova

Affiliations Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

Jiang Liu

Affiliation Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

Joseph T. Roland

Affiliations Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

Chin Chiang

Affiliation Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

James R. Goldenring

jim.goldenring@vanderbilt.edu

Affiliations Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

Competing Interests

This work was supported in part by funding from Ziopharm, who is the maker of Darinaparsin. The funding was an unrestricted research grant to Dr. Kolobova. No other financial interactions are involved. This funding from Ziopharm does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: TAM EK JL JTR CC JRG. Performed the experiments: TAM EK JL JTR JRG. Analyzed the data: TAM EK JL JTR CC JRG. Wrote the paper: TAM EK JL CC JRG.