About the Authors

Takeshi Moriishi

Affiliation Department of Cell Biology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan

Zenjiro Maruyama

Affiliations Department of Cell Biology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan, Department of Sensory and Motor System Medicine, University of Tokyo, Tokyo, Japan

Ryo Fukuyama

Affiliation Laboratory of Pharmacology, Hiroshima International University, Kure, Japan

Masako Ito

Affiliation Department of Radiology and Radiation Biology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan

Toshihiro Miyazaki

Affiliation Department of Cell Biology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan

Hideki Kitaura

Affiliations Division of Orthodontic and Biomedical Engineering, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan, Division of Orthodontics and Dentofacial Orthopedics, Graduate School of Dentistry, Tohoku University, Sendai, Japan

Hidetake Ohnishi

Affiliations Department of Cell Biology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan, Department of Orthodontics and Dentofacial Orthopedics, Faculty of Dentistry, Osaka University, Osaka, Japan

Tatsuya Furuichi

Affiliations Department of Cell Biology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan, Laboratory Animal Facility, Research Center for Medical Sciences, School of Medicine, Jikei University, Tokyo, Japan

Yosuke Kawai

Affiliations Department of Cell Biology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan, Department of Regenerative Oral Surgery, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan

Ritsuko Masuyama

Affiliation Department of Cell Biology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan

Hisato Komori

Affiliation Department of Cell Biology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan

Kenji Takada

Affiliation Department of Orthodontics and Dentofacial Orthopedics, Faculty of Dentistry, Osaka University, Osaka, Japan

Hiroshi Kawaguchi

Affiliation Department of Sensory and Motor System Medicine, University of Tokyo, Tokyo, Japan

Toshihisa Komori

komorit@nagasaki-u.ac.jp

Affiliation Department of Cell Biology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TK. Performed the experiments: T. Moriishi ZM RF MI T. Miyazaki H. Kitaura HO TF YK RM H. Komori. Analyzed the data: KT H. Kawaguchi. Wrote the paper: TK.