About the Authors

Cheryl R. Clark

crclark@partners.org

Affiliations Division of General Medicine and Primary Care, Brigham and Women's-Faulkner Hospitalist Program, Harvard Medical School, Boston, Massachusetts, United States of America, Center for Community Health and Health Equity, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

Brent Coull

Affiliation Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America

Lisa F. Berkman

Affiliations Harvard Center for Population and Development Studies, Harvard School of Public Health, Boston, Massachusetts, United States of America, Department of Society, Human Development and Health, Harvard School of Public Health, Boston, Massachusetts, United States of America

Julie E. Buring

Affiliation Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

Paul M. Ridker

Affiliations Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Center for Cardiovascular Disease Prevention, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Division of Cardiovascular Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Competing Interests

Dr. Ridker is listed as a co-inventor on patents held by the Brigham and Women's Hospital that relate to the use of inflammatory biomarkers in cardiovascular disease that have been licensed to Siemens and AstraZeneca. The US patent numbers and names are: US Patent No. 6,040,147. Means of ascertaining an individual's risk profile for atherosclerotic disease (Ridker PM, Hennekens CH). US Patent No. 7,030,152. Systemic inflammatory markers as diagnostic tools in the prevention of atherosclerotic events. (Ridker PM, Hennekens CH). This does not alter the authors' adherence to the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: CRC LFB PMR BC. Analyzed the data: CRC BC. Contributed reagents/materials/analysis tools: JEB PMR CRC. Wrote the paper: CRC PMR BC. Analysis or interpretation of data: CRC BC LFB PMR. Critical review and editing of manuscript: CRC BC LFB JEB PMR.